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OWise-breast cancer is developed by Px Healthcare.

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Watch the OWise Launch video and hear what patients think of it.
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About Px HealthCare
Px HealthCare develops mobile health solutions for people with chronic diseases providing them with individualised, practical support as well as self-reporting tools. This is likely to improve the dialogue between the patient and the treating clinician and the patient-reported data enables the doctor to adjust the treatment more effectively when necessary. At the same time, the fully anonimised user data (Px does not have any personal details of the users) will be used in aggregated form to conduct health outcomes research.
 
The focus of the company is initially on breast cancer as so many women are affected by the condition and the impact, both mentally and physically, is big. However expansion of the product line into other cancer types is planned for the near future. Through the website (www.owise.nl) and the OWise mobile app, Px HealthCare offers women (and men) smart internet tools which helps them gaining insight into and control over their situation during and after illness.
 
As a research organisation Px HealthCare aims to improve the treatment and diagnosis of (breast) cancer by conducting high-quality research into disease subtype, treatments, lifestyle, environmental and genetic factors. The company collects the fully anonimised data that users enter via the app and website and uses the aggregated data for medical research. By doing so the company can identify correlations between medication and side-effects, as well as drug-drug interactions in a real life setting. Longer term, Px HealthCare aims to obtain insight into how environmental factors affect the genome and how diseases such as breast cancer can be possibly prevented or treated more effectively. More about the medical research goals of the company can be read below.
 
Px HealthCare is a life sciences company, founded in 2012, which puts 'patients first' by providing them with support tools that make a real difference to their quality of life. As a data-analytics company, the longitudinal and clinical field data collected enable the company to gain essential insight into the effectiveness of treatments for cancer. Px HealthCare's goals are to
 
The company was founded by Dr. Anne Bruinvels who devoted much of her international career to the development of more effective, personalised drug treatments and diagnostic tools. The 'Px' of Px HealthCare stands for personalised.
 
Px HealthCare is based in Amsterdam, the Netherlands but has an international focus. While products are initially developed and tested in the Netherlands (the country with the highest proportion of the population being online), they will be rolled out in other European (and non-European) countries in the near future. The collection of data worldwide will be extremely useful for conducting health outcomes research and for obtaining a better understanding of the factors that contribute to the development of illnesses such as cancer and other chronic diseases. If you would you like to receive more information on Px HealthCare please send an e-mail to info@pxhealthcare.com.
 
Px HealthCare and medical research
It is known that approximately 5 to 8% of women with breast cancer have a genetic predisposition. However, for the vast majority of women with breast cancer its causes are not well understood. Scientists believe that a multitude of factors play a role, with the 'unfortunate' combination of such factors causing breast cancer. There is evidence that factors such as starting to menstruate at an early age or pregnancy at a late age may play a role, but this does not explain whether or what type of breast cancer one may get. In addition to genetic factors environmental factors (where one lives, what habits a person has) may have an effect on a person's genetic material (DNA), which may in turn result in the development of breast cancer. 
 
In the long term Px HealthCare aims to better understand how environmental factors affect a person's DNA. This is a scientific field called epigenetics. Our long-term goal is to study the influence of environmental factors on the DNA in people with diseases such as breast cancer to to identify the mechanisms that cause breast cancer. We do however require full informed consent from those OWise users to contribute to this research. 
 
In the short term Px HealthCare will investigate the occurrence of adverse events related to prescription drugs and the effects of different drug combinations in diseases such as breast cancer.  Also the impact of certain lifestyle factors will be studied. The user data is completely anonymous. This means that Px HealthCare does not have full names of the users nor their dates of birth. E-mail addresses are one-way encrypted and are therefore not kept in the company's files. Further all login details are kept strictly separated from the user data.
 
The user data are owned by an independent foundation, called Px for Life. The purpose of the foundation is to protect and safeguard the user data at all times.
 
Management of Px HealthCare 
The company is led by a small team consisting of:
 
Anne Bruinvels, PhD: Founder, General Affairs
David Bruinvels, MD, PhD: Medical Affairs & IT
Deb Ain, (MA): Communications
 
A Scientific and Medical Advisory Board is currently being established. The company is also setting up a number of collaborations with various Dutch hospitals to evaluate the Dutch version of OWise breast cancer. Information on these developments will be published soon on this website.
 
Px HealthCare B.V. is an independent organisation fully funded by its shareholders. For further information please contact:
Dr. Anne T. Bruinvels, e-mail: anneb@pxhealthcare.com
Or visit www.pxhealthcare.com
 

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